Abstract
Two novel side chains which had previously been found to enhance antagonist activity in the dihydrobenzoxathiin SERM series were applied to three existing platforms. The novel side chains did not improve the antagonist activity of the existing platforms.
MeSH terms
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Animals
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Estrogen Receptor alpha / antagonists & inhibitors*
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Ligands
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Oxathiins / chemistry*
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Rats
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Selective Estrogen Receptor Modulators / chemistry*
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Selective Estrogen Receptor Modulators / pharmacology*
Substances
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Estrogen Receptor alpha
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Ligands
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Oxathiins
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Selective Estrogen Receptor Modulators
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dihydrobenzoxathiin